Fixed Effects vs. Random Effects Meta- Analysis Models: Implications for Cumulative Research Knowledge

نویسندگان

  • John E. Hunter
  • Frank L. Schmidt
چکیده

Research conclusions in the social sciences are increasingly based on meta-analysis, making questions of the accuracy of meta-analysis critical to the integrity of the base of cumulative knowledge. Both fixed effects (FE) and random effects (RE) meta-analysis models have been used widely in published meta-analyses. This article shows that FE models typically manifest a substantial Type I bias in significance tests for mean effect sizes and for moderator variables (interactions), while RE models do not. Likewise, FE models, but not RE models, yield confidence intervals for mean effect sizes that are narrower than their nominal width, thereby overstating the degree of precision in meta-analysis findings. This article demonstrates analytically that these biases in FE procedures are large enough to create serious distortions in conclusions about cumulative knowledge in the research literature. We therefore recommend that RE methods routinely be employed in meta-analysis in preference to FE methods.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fixed- versus random-effects models in meta-analysis: model properties and an empirical comparison of differences in results.

Today most conclusions about cumulative knowledge in psychology are based on meta-analysis. We first present an examination of the important statistical differences between fixed-effects (FE) and random-effects (RE) models in meta-analysis and between two different RE procedures, due to Hedges and Vevea, and to Hunter and Schmidt. The implications of these differences for the appropriate interp...

متن کامل

Comparison between Multivariate Fixed-Effects and Mixed-Effects Meta-Analytic Approaches

The use of different multivariate meta-analytic approaches to quantitatively combine and aggregate effect sizes from different primary studies can have different important implications for the cumulative research findings and research-based conclusions. Multivariate fixed and mixed effects (multivariate random-effects regression) models are examples for such approaches. Gaining knowledge of the...

متن کامل

Discovery properties of genome-wide association signals from cumulatively combined data sets.

Genetic effects for common variants affecting complex disease risk are subtle. Single genome-wide association (GWA) studies are typically underpowered to detect these effects, and combination of several GWA data sets is needed to enhance discovery. The authors investigated the properties of the discovery process in simulated cumulative meta-analyses of GWA study-derived signals allowing for pot...

متن کامل

Clinical comparison of Persica and Chlorhexidine mouthrinses using meta – analysis technique

Clinical comparison of Persica and Chlorhexidine mouthrinses using meta – analysis technique Dr. H. Fallahzadeh* - Dr. A. Moeintaghavi** - Dr. M. Foruzanmehr*** *-Assistant Professor of Epidemiology and Statistics Dept.-Faculty of Hygiene-Shaheed Sadoughi Yazd University of Medical Sciences. **- Assistant Professor of Periodontology Dept. - Faculty of Dentistry – Mashhad University of Medical S...

متن کامل

Predicting Iran's economic growth rate using meta-analysis method

One of the most important issues for governments to maintain and improve their position in the regional and global economy is the state of economic growth; one of the important issues in this situation is to predict the rate of economic growth. Proper forecasting of economic growth has very important effects on government policy and economic planning, and can help policymakers decide on future ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2000